Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial

JW Murrough, DV Iosifescu, LC Chang… - American Journal of …, 2013 - Am Psychiatric Assoc
… , treatment-resistant patients in a major depressive episode … rapid antidepressant response
to a single infusion of ketamine. … study represents the largest investigation to date of ketamine

Single, repeated, and maintenance ketamine infusions for treatment-resistant depression: a randomized controlled trial

JL Phillips, S Norris, J Talbot… - American Journal of …, 2019 - Am Psychiatric Assoc
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site
randomized controlled trial. Am J … A randomized trial of an N-methyl-d-aspartate antagonist in …

Cognitive behavioral therapy to sustain the antidepressant effects of ketamine in treatment-resistant depression: a randomized clinical trial

ST Wilkinson, TG Rhee, J Joormann… - Psychotherapy and …, 2021 - karger.com
randomized trial to examine the feasibility and efficacy of cognitive behavioral therapy (CBT)
following intravenous ketamine in treatment-resistant depression (… severe major depressive

A randomized controlled trial of intranasal ketamine in major depressive disorder

KAB Lapidus, CF Levitch, AM Perez, JW Brallier… - Biological …, 2014 - Elsevier
… The N-methyl-D-aspartate glutamate receptor antagonist ketamine, delivered via an
intravenous route, has shown rapid antidepressant effects in patients with treatment-resistant

Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

M Fava, MP Freeman, M Flynn, H Judge… - Molecular …, 2020 - nature.com
… -controlled study of the acute efficacy of IV ketamine or … adequate ADTs during the current
major depressive episode (TRD). … of antidepressant efficacy of all doses of ketamine vs. active …

A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant …

PR Shiroma, P Thuras, J Wels, CS Albott… - Translational …, 2020 - nature.com
… Repeated ketamine showed greater antidepressant efficacy … in a randomized controlled
trial in treatment-resistant major … among subjects with treatment-resistant major depression. …

Single, repeated, and maintenance ketamine infusions for treatment-resistant depression: a randomized controlled trial

JL Phillips, S Norris, J Talbot, M Birmingham… - Focus, 2020 - Am Psychiatric Assoc
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site
randomized controlled trial. Am J … A randomized trial of an N-methyl-d-aspartate antagonist in …

Neurocognitive effects of ketamine and association with antidepressant response in individuals with treatment-resistant depression: a randomized controlled trial

JW Murrough, KE Burdick, CF Levitch… - …, 2015 - nature.com
ketamine and neurocognition in the context of a two-site, double-blind, … Antidepressant
efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial

Effects of ketamine on explicit and implicit suicidal cognition: A randomized controlled trial in treatmentresistant depression

RB Price, DV Iosifescu, JW Murrough… - Depression and …, 2014 - Wiley Online Library
… Symptomatic patients with treatment-resistant unipolar major depression (inadequate … for
a two-site double-blind randomized controlled trial (RCT) of ketamine's antidepressant efficacy, …

Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression

CA Farmer, JR Gilbert, R Moaddel, J George… - …, 2020 - nature.com
… ), a racemic mixture comprising (S)- and (R)-ketamine, produces antidepressant … with major
depressive disorder (MDD) [1], bipolar depression [2, 3], and treatment-resistant depression (…